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ML SA1

CAS No. 332382-54-4

ML SA1 ( Mucolipin synthetic agonist 1 )

产品货号. M24271 CAS No. 332382-54-4

ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥381 有现货
10MG ¥599 有现货
25MG ¥1247 有现货
50MG ¥2074 有现货
100MG ¥3110 有现货
200MG ¥4682 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    ML SA1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity.
  • 产品描述
    ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively[1].
  • 同义词
    Mucolipin synthetic agonist 1
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    TRPML
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    332382-54-4
  • 分子量
    362.4
  • 分子式
    C22H22N2O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:17 mg/mL (46.90 mM)
  • SMILES
    CC(CC1(C)C)c(cccc2)c2N1C(CN(C(c1c2cccc1)=O)C2=O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Xia Z, et al. ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity. Antiviral Res. 2020;182:104922.
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